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At the Swiss-Prot Group we develop, annotate and maintain the UniProtKB/Swiss-Prot protein sequence database, the most widely used protein information resource in the world. Data recovery external hard drive We also develop and maintain other databases including PROSITE, a database of protein families and domains, ENZYME, a database of enzyme nomenclature, HAMAP , a collection of manually curated family profiles for protein classification, and associated, manually created annotation rules, Rhea, a curated database of chemical reactions and SwissLipids, an expert-curated resource that integrates lipidomics data with biological knowledge. Database 1 to many We also offer to the virologists community the ViralZone portal. Data recovery galaxy s6 The group also co-heads the development and maintenance of the ExPASy proteomics website.

Os x data recovery software We are one of the largest groups in the Swiss Institute of Bioinformatics. Database technology Highlights 2016

Our group continues to produce and maintain the Swiss-Prot section of the UniProt knowledgebase, adding expert-curated knowledge from over 7000 new publications describing over 3300 new proteins and functions. Database queries definition Expert curation is essential to the development of Swiss-Prot, and remains the surest means of providing life science researchers with rapid access to comprehensive knowledge on protein function. Data recovery mac free In 2016 we performed a detailed and wide ranging investigation of published and curated literature in Swiss-Prot. Data recovery phone This investigation revealed that the expert curation of UniProtKB/Swiss-Prot provides high coverage of available knowledge and that this activity is both scalable and sustainable.

While the majority of our efforts are directed at UniProtKB/Swiss-Prot, our group continues to develop a range of complementary and specialized knowledge resources for life scientists. Database normalization These include the Rhea knowledgebase of expert curated biochemical reactions which has applications in enzyme annotation (Rhea will be used in UniProt from 2017 onwards) and the description of genome scale metabolic networks (Rhea is a reference resource for MetaNetX at Vital-IT). Data recovery quote We introduced a new reaction classification which complements and extends the widely-used enzyme classification of the IUBMB. Database key types Rhea currently describes over 9500 unique reactions curated from a similar number of publications.Our ViralZone team worked with collaborators from the University of KwaZulu-Natal to develop an improved resource for the life scientists working on HIV-1, the BioAfrica HIV-1 Proteome Resource. Database instance We collaborated with a number of SIB groups and other world renowned institutes on the development of standardized benchmarks for the phylogenetic inference, a cornerstone for both evolutionary studies and functional annotation efforts.

Our group continues our SIB outreach and educational activities. Data recovery raid 0 The web-team plays an active and extensive role in the development of the SIB bioinformatics resource portal ExPASy. Data recovery tools Main publications 2016

• Morgat A et al. Database programming languages Updates in Rhea – an expert curated resource of biochemical reactions. Super 8 database Nucleic Acids Res (Database issue) 2016; pii:gkw990.